<p>This domain has a distorted supersandwich structure consisting of 18 strands in two sheets, and probably functions to bind carbohydrates in enzymes that act on sugars. Domains with this structure occur in several protein families, including galactose mutarotase (<db_xref db="EC" dbkey="5.1.3.3"/>) [<cite idref="PUB00010717"/>]; domain 5 of beta-galactosidase (<db_xref db="EC" dbkey="3.2.1.23"/>); the central domain of hyaluronate lyase-like enzymes, such as chondroitinase AC (<db_xref db="EC" dbkey="4.2.2.5"/>), xanthan lyase (<db_xref db="EC" dbkey="4.2.2.12"/>), chrondroitin ABC lyase I, and hyaluronate lyase (<db_xref db="EC" dbkey="4.2.2.1"/>) itself [<cite idref="PUB00014072"/>]; the N-terminal domain of lactobacillus maltose phosphorylase (<db_xref db="EC" dbkey="2.4.1.8"/>) and bacterial glucoamylase (<db_xref db="EC" dbkey="3.2.1.3"/>) [<cite idref="PUB00008368"/>, <cite idref="PUB00014073"/>]; the C-terminal domain of eukaryotic alpha-mannosidase (<db_xref db="EC" dbkey="3.2.1.24"/>) and archaeon 4-alpha-glucanotransferase (<db_xref db="EC" dbkey="2.4.1.25"/>) [<cite idref="PUB00014074"/>].</p> Glycoside hydrolase-type carbohydrate-binding